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Pro-hevein (Alternative name: Major hevein, gene name: HEV1) is a wound-induced and a lectin-like protein from ''Hevea brasiliensis'' (rubber tree) where it is involved in the coagulation of latex. The 187 amino-acid propeptide pro-hevein is cleaved in two fragments: a N-terminal 43 amino-acid Hevein bearing a chitin-binding type-1 domain (also known as CBM18 carbohydrate-binding module) that binds to chitin and a 138 amino-acid Win-like protein bearing a Barwin domain. It has antifungal properties. == Role of hevein in latex allergy == Hevein is the main IgE-binding epitope of the major latex allergen prohevein as are hevein-like protein domains in fruit class I chitinases. Therefore it is a possible cause for allergen cross-reactivity between latex and banana or other fruits like chestnuts or avocadoes. Hevein-like genes can be found in many plants including ''Arabidopsis thaliana''. The conformational epitope on hevein is called ''Hev b 6.02''. 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「Pro-hevein」の詳細全文を読む スポンサード リンク
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